Real Peptides PE-22-28
$54.99
PE22-28 is a synthetic seven-amino acid peptide corresponding to residues 22 to 28 of spadin, a fragment released from the propeptide of sortilin (neurotensin receptor 3). It has been characterized in preclinical research as a selective TREK-1 potassium channel blocker, making it a useful tool compound for isolating channel-mediated neuronal signaling endpoints in experimental designs.
PE22-28 has been used in preclinical in vitro and rodent model studies to investigate TREK-1 channel inhibition, hippocampal neurogenesis, synaptic plasticity, and rodent behavioral assay endpoints. Its shortened sequence and higher channel affinity relative to spadin support mechanistic characterization of two-pore potassium channel biology in cell-based and rodent research.
Intended use: In vitro and preclinical in vivo laboratory research only. Not approved for human or veterinary use.
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The information, including discussions about specific peptides and their researched benefits, is presented for informational purposes only and must not be construed as health, clinical, or legal guidance, nor an encouragement for non-research use in humans.
Peptides described here are solely for use in structured scientific study by authorized individuals. We advise consulting with research experts, medical practitioners, or legal counsel prior to any decisions about obtaining or utilizing these peptides.
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